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Genetic Analysis

Single Nucleotide Polymorphism (SNP) Analysis

  • Identification of nonsynonymous Single Nucleotide Polymorphisms (nsSNPs)

  • Functional analysis of nonsynonymous SNPs

  • Effect of Mutation on Protein Stability

  • Evaluation of evolutionary stability of protein

  • Protein solvent accessibility and prediction of secondary structure

For further enquiries, please contact us

  • Singh SK, Reddy SM. Homology modelling, docking, ADMET studies and prediction of deleterious nonsynonymous single nucleotide polymorphisms (nsSNPs) of thiamin phosphate synthase: a potential drug target in Plasmodium falciparum. Indian J Pharm Sci (In press).

  • Singh SK, Reddy SM. Investigation of hub genes and their nonsynonymous single nucleotide polymorphism analysis in Plasmodium falciparum for designing therapeutic methodologies using next-generation sequencing approach. Indian J Pharmacol 2019; 51:389-99.

  • Firoz A, Malik A, Singh SK, Jha V, Ali A. Identification of hub glycogenes and their nsSNP analysis from mouse RNA-Seq data. Gene. 2015; 574:235-46.

  • Firoz A, Malik A, Singh SK, Jha V, Ali A. Comparative Analysis of Glycogene Expression in Different Mouse Tissues Using RNA-Seq Data. Int J Genomics. 2014; 2014:837365.